Emerging Researchers’ Workshop – registration required (Level 2)
- 08:00 – 08:30 Registration & Networking & High Tea Breakfast
- 08:30 – 08:40 Welcome & Introductions Chari Cohen, Thomas Tu & Nina Le Bert
- 08:40 – 09:10 Icebreaker Activity
- 09:10 – 10:30 Panel & Audience Discussion on “Navigating Transition Phases in Your Research Career” Moderator: Jochen Wettengel Panel: Haitao Guo, Rachel Jeng, Wenhui Li, Lefteris Michailidis, Alexander Ploss, Ulrike Protzer
- 10:30 – 10:45 Break
- 10:45 – 12:00 Table Discussions: Table Discussions: Peer-to-peer discussion of topics related to transition phases in research careers
Lunch & Networking with Panelists and Peers (Level 2)
HBF and ICE-HBV Community Forum - registration required (Level 4 + 5)
- 13:00 – 13:05 Welcome and Opening Remarks, Chari Cohen, DrPH, MPH
- 13:05 – 13:25 Epidemiology, Progress and Challenges with Hepatitis B Elimination in Southeast Asia, Seng Gee Lim, FRACP, FRCP, FAMS, MD
- 13:25 – 13:45 Progress towards Hepatitis B Elimination in Vietnam, Doan Dao, MD
- 13:45 – 14:15 Lived experience of hepatitis B or D in Asia – Panel Discussion, Panelists: Chris, Dee, Lien and Tay
- 14:15 – 14:25 Q&A, Moderated by Catherine Freeland
- 14:25 – 14:30 Closing Remarks, Maura Dandri, MD, PhD
High Tea for Community Forum & ICE-HBV Symposium (Level 4 + 5)
The 7th ICE-HBV Symposium: Therapeutic Vaccines for Chronic Hepatitis B: Optimizing Their Utility in Novel Therapeutic Combinations - registration required (Level 4 + 5)
- 15:00 – 15:10 Welcome & Opening Remarks, Chairs: Adam J Gehring & Anna D. Kosinska
- 15:10 – 15:35 What we’ve learned, current strategies and future prospects for therapeutic vaccines, Speaker: Anna Kosinska
- 15:35 – 16:00 Vaccine combinations in the current landscape of novel HBV therapies, Speaker: Seng Gee Lim
- 16:00 – 16:25 What deep translational studies teach us about vaccine efficacy in combination therapies, experience from the Brii studies Speaker: Antonio Bertoletti
- Coffee and Tea Break (Level 4 + 5)
- 16:45 – 17:05 How much would effective therapeutic vaccination improve functional cure rates? Speaker: Adam Gehring
- 17:05 – 17:15 TherVacB - on the way to the clinic Speaker: Ulrike Protzer
- 17:15 – 17:25 Immunogenicity and antiviral efficacy of GS-2829 and GS-6779 in CHB patients with a broad range of baseline HBsAg levels Speaker: Simon Fletcher
- 17:25 – 17:35 Immunogenicity and long-term antiviral effect of VRON-0200 Speaker: Sue Currie
- 17:35 – 18:00 Round Table Discussion & Closing of ICE-HBV Symposium
Welcome Reception: Refreshing Drinks & Asian Live Food Stations
Morning Coffee & Networking (Level 4 + 5)
Lion Dance & Welcome Address (Level 4 + 5)
Thomas Tu, Associate Professor, Westmead Clinical School, University of Sydney, Australia & Nina Le Bert, Assistant Professor, Duke-NUS Medical School, Singapore
Distinguished Award in Hepatitis B Research Lecture – John E. Tavis, PhD
Moderator: Haitao Guo; Introduction of the Awardee by Fabien Zoulim
Morning Coffee & Networking (Level 4 + 5)
Session 1: New Models (Level 4 + 5)
Session Chairs: Robert Schwartz & Helene Strick-Marchand
- 11:00 – 11:12 Establishment of an immunocompetent mouse model of hepadnavirus infection using Asian grey shrew hepatitis B virus Chen Li
- 11:12 – 11:17 Q&A
- 11:17 – 11:29 A late entry step restricts hepatitis B virus infection in murine hepatocytes Xupeng Hong
- 11:29 – 11:34 Q&A 11:34 – 11:46 Oncostatin M and forskolin confer permissiveness to HBV infection in A549-NTCP lung carcinoma cells Yi Ni
- 11:46 – 11:51 Q&A 11:51 – 12:03 A rice rat hepadnavirus efficiently replicates and forms cccDNA in cotton rat and mouse hepatocytes Qingyan Wu
- 12:03 – 12:08 Q&A 12:08 – 12:20 Modeling hepatitis B driven hepatocarcinogenesis in zebrafish Samer Ayoub
- 12:20 – 12:25 Q&A
Sponsors & Travel Awards (Level 4 + 5)
Buffet Lunch & Networking (Level 2 + 4)
Keynote Lecture 1 (Level 4 + 5)
Speaker: Julia Beatty
14:00 - 14:30 Lecture: "Cancer-causing viruses in cats (and how they will save the world)"
14:34 - 14:40 Q & A
Grand Discussion Round 1 - Animal models of Hepatitis B: what we have, how they can inform us, and where we need to go from here
Panelists: Ulrike Protzer, Luca Guidotti, Maura Dandri, Carla Coffin, Ben Burowitz, Julia Beatty; Moderator: Thomas Tu
Afternoon Coffee & Networking (Level 4 + 5)
Session 2: HBV Pathogenesis (Level 4 + 5)
Session Chairs: Adam Gehring & Margaret Littlejohn
- 16:00 – 16:12 Spatial profiling the chronic hepatitis B liver identifies viralimmune niches that perturb local immune responses in a zonal dependent manner James Harris
- 16:12 – 16:17 Q&A
- 16:17 – 16:29 Visualizing the spatial dynamics of in situ HBV-specific tissueresident memory T cells and hepatic immune niches that govern tumor control in hepatocellular carcinoma Jing-Yun Wu
- 16:29 – 16:34 Q&A
- 16:34 – 16:46 Kupffer cells modulate the early host immune response and severity of hepatitis in the woodchuck infection model of hepatitis B Md Deen Islam
- 16:46 – 16:51 Q&A
- 16:51 – 17:03 Hepatic Tertiary Lymphoid Structures Enable Local Adaptive Immune Responses in the HBV-Replicating Liver Cristian G Beccaria
- 17:03 – 17:08 Q&A 17:08 – 17:20 Proliferation of hepatocytes in postnatal period depletes nuclear cccDNA in vivo Qiong Li
- 17:20 – 17:25 Q&A 1
- 7:25 – 17:37 Visualization of HBV by Metabolic Glycan Labeling Yi Wang
- 17:37 – 17:42 Q&A
Poster Session 1 (Level 2)
High Tea & Drinks
Emerging Researcher’s Dinner
By Invitation Only RSVP Required
Emerging Researchers’ Workshop – registration required (Level 2)
- 08:00 – 08:30 Registration & Networking & High Tea Breakfast
- 08:30 – 08:40 Welcome & Introductions Chari Cohen, Thomas Tu & Nina Le Bert
- 08:40 – 09:10 Icebreaker Activity
- 09:10 – 10:30 Panel & Audience Discussion on “Navigating Transition Phases in Your Research Career” Moderator: Jochen Wettengel Panel: Haitao Guo, Rachel Jeng, Wenhui Li, Lefteris Michailidis, Alexander Ploss, Ulrike Protzer
- 10:30 – 10:45 Break
- 10:45 – 12:00 Table Discussions: Table Discussions: Peer-to-peer discussion of topics related to transition phases in research careers
Lunch & Networking with Panelists and Peers (Level 2)
HBF and ICE-HBV Community Forum - registration required (Level 4 + 5)
- 13:00 – 13:05 Welcome and Opening Remarks, Chari Cohen, DrPH, MPH
- 13:05 – 13:25 Epidemiology, Progress and Challenges with Hepatitis B Elimination in Southeast Asia, Seng Gee Lim, FRACP, FRCP, FAMS, MD
- 13:25 – 13:45 Progress towards Hepatitis B Elimination in Vietnam, Doan Dao, MD
- 13:45 – 14:15 Lived experience of hepatitis B or D in Asia – Panel Discussion, Panelists: Chris, Dee, Lien and Tay
- 14:15 – 14:25 Q&A, Moderated by Catherine Freeland
- 14:25 – 14:30 Closing Remarks, Maura Dandri, MD, PhD
High Tea for Community Forum & ICE-HBV Symposium (Level 4 + 5)
The 7th ICE-HBV Symposium: Therapeutic Vaccines for Chronic Hepatitis B: Optimizing Their Utility in Novel Therapeutic Combinations - registration required (Level 4 + 5)
- 15:00 – 15:10 Welcome & Opening Remarks, Chairs: Adam J Gehring & Anna D. Kosinska
- 15:10 – 15:35 What we’ve learned, current strategies and future prospects for therapeutic vaccines, Speaker: Anna Kosinska
- 15:35 – 16:00 Vaccine combinations in the current landscape of novel HBV therapies, Speaker: Seng Gee Lim
- 16:00 – 16:25 What deep translational studies teach us about vaccine efficacy in combination therapies, experience from the Brii studies Speaker: Antonio Bertoletti
- Coffee and Tea Break (Level 4 + 5)
- 16:45 – 17:05 How much would effective therapeutic vaccination improve functional cure rates? Speaker: Adam Gehring
- 17:05 – 17:15 TherVacB - on the way to the clinic Speaker: Ulrike Protzer
- 17:15 – 17:25 Immunogenicity and antiviral efficacy of GS-2829 and GS-6779 in CHB patients with a broad range of baseline HBsAg levels Speaker: Simon Fletcher
- 17:25 – 17:35 Immunogenicity and long-term antiviral effect of VRON-0200 Speaker: Sue Currie
- 17:35 – 18:00 Round Table Discussion & Closing of ICE-HBV Symposium
Welcome Reception: Refreshing Drinks & Asian Live Food Stations
Emerging Researchers’ Workshop – registration required (Level 2)
- 08:00 – 08:30 Registration & Networking & High Tea Breakfast
- 08:30 – 08:40 Welcome & Introductions Chari Cohen, Thomas Tu & Nina Le Bert
- 08:40 – 09:10 Icebreaker Activity
- 09:10 – 10:30 Panel & Audience Discussion on “Navigating Transition Phases in Your Research Career” Moderator: Jochen Wettengel Panel: Haitao Guo, Rachel Jeng, Wenhui Li, Lefteris Michailidis, Alexander Ploss, Ulrike Protzer
- 10:30 – 10:45 Break
- 10:45 – 12:00 Table Discussions: Table Discussions: Peer-to-peer discussion of topics related to transition phases in research careers
Lunch & Networking with Panelists and Peers (Level 2)
HBF and ICE-HBV Community Forum - registration required (Level 4 + 5)
- 13:00 – 13:05 Welcome and Opening Remarks, Chari Cohen, DrPH, MPH
- 13:05 – 13:25 Epidemiology, Progress and Challenges with Hepatitis B Elimination in Southeast Asia, Seng Gee Lim, FRACP, FRCP, FAMS, MD
- 13:25 – 13:45 Progress towards Hepatitis B Elimination in Vietnam, Doan Dao, MD
- 13:45 – 14:15 Lived experience of hepatitis B or D in Asia – Panel Discussion, Panelists: Chris, Dee, Lien and Tay
- 14:15 – 14:25 Q&A, Moderated by Catherine Freeland
- 14:25 – 14:30 Closing Remarks, Maura Dandri, MD, PhD
High Tea for Community Forum & ICE-HBV Symposium (Level 4 + 5)
The 7th ICE-HBV Symposium: Therapeutic Vaccines for Chronic Hepatitis B: Optimizing Their Utility in Novel Therapeutic Combinations - registration required (Level 4 + 5)
- 15:00 – 15:10 Welcome & Opening Remarks, Chairs: Adam J Gehring & Anna D. Kosinska
- 15:10 – 15:35 What we’ve learned, current strategies and future prospects for therapeutic vaccines, Speaker: Anna Kosinska
- 15:35 – 16:00 Vaccine combinations in the current landscape of novel HBV therapies, Speaker: Seng Gee Lim
- 16:00 – 16:25 What deep translational studies teach us about vaccine efficacy in combination therapies, experience from the Brii studies Speaker: Antonio Bertoletti
- Coffee and Tea Break (Level 4 + 5)
- 16:45 – 17:05 How much would effective therapeutic vaccination improve functional cure rates? Speaker: Adam Gehring
- 17:05 – 17:15 TherVacB - on the way to the clinic Speaker: Ulrike Protzer
- 17:15 – 17:25 Immunogenicity and antiviral efficacy of GS-2829 and GS-6779 in CHB patients with a broad range of baseline HBsAg levels Speaker: Simon Fletcher
- 17:25 – 17:35 Immunogenicity and long-term antiviral effect of VRON-0200 Speaker: Sue Currie
- 17:35 – 18:00 Round Table Discussion & Closing of ICE-HBV Symposium
Welcome Reception: Refreshing Drinks & Asian Live Food Stations
Emerging Researchers’ Workshop – registration required (Level 2)
- 08:00 – 08:30 Registration & Networking & High Tea Breakfast
- 08:30 – 08:40 Welcome & Introductions Chari Cohen, Thomas Tu & Nina Le Bert
- 08:40 – 09:10 Icebreaker Activity
- 09:10 – 10:30 Panel & Audience Discussion on “Navigating Transition Phases in Your Research Career” Moderator: Jochen Wettengel Panel: Haitao Guo, Rachel Jeng, Wenhui Li, Lefteris Michailidis, Alexander Ploss, Ulrike Protzer
- 10:30 – 10:45 Break
- 10:45 – 12:00 Table Discussions: Table Discussions: Peer-to-peer discussion of topics related to transition phases in research careers
Lunch & Networking with Panelists and Peers (Level 2)
HBF and ICE-HBV Community Forum - registration required (Level 4 + 5)
- 13:00 – 13:05 Welcome and Opening Remarks, Chari Cohen, DrPH, MPH
- 13:05 – 13:25 Epidemiology, Progress and Challenges with Hepatitis B Elimination in Southeast Asia, Seng Gee Lim, FRACP, FRCP, FAMS, MD
- 13:25 – 13:45 Progress towards Hepatitis B Elimination in Vietnam, Doan Dao, MD
- 13:45 – 14:15 Lived experience of hepatitis B or D in Asia – Panel Discussion, Panelists: Chris, Dee, Lien and Tay
- 14:15 – 14:25 Q&A, Moderated by Catherine Freeland
- 14:25 – 14:30 Closing Remarks, Maura Dandri, MD, PhD
High Tea for Community Forum & ICE-HBV Symposium (Level 4 + 5)
The 7th ICE-HBV Symposium: Therapeutic Vaccines for Chronic Hepatitis B: Optimizing Their Utility in Novel Therapeutic Combinations - registration required (Level 4 + 5)
- 15:00 – 15:10 Welcome & Opening Remarks, Chairs: Adam J Gehring & Anna D. Kosinska
- 15:10 – 15:35 What we’ve learned, current strategies and future prospects for therapeutic vaccines, Speaker: Anna Kosinska
- 15:35 – 16:00 Vaccine combinations in the current landscape of novel HBV therapies, Speaker: Seng Gee Lim
- 16:00 – 16:25 What deep translational studies teach us about vaccine efficacy in combination therapies, experience from the Brii studies Speaker: Antonio Bertoletti
- Coffee and Tea Break (Level 4 + 5)
- 16:45 – 17:05 How much would effective therapeutic vaccination improve functional cure rates? Speaker: Adam Gehring
- 17:05 – 17:15 TherVacB - on the way to the clinic Speaker: Ulrike Protzer
- 17:15 – 17:25 Immunogenicity and antiviral efficacy of GS-2829 and GS-6779 in CHB patients with a broad range of baseline HBsAg levels Speaker: Simon Fletcher
- 17:25 – 17:35 Immunogenicity and long-term antiviral effect of VRON-0200 Speaker: Sue Currie
- 17:35 – 18:00 Round Table Discussion & Closing of ICE-HBV Symposium